From data on 25,544 patients on ADT in New Zealand, 10.8% broke at least one bone compared to only 3.2% of men not on ADT. Increased risk of fractures remains one of the most serious side effects of ADT and a reason why patients on ADT need to be attentive to their bone health.
Wang A, Obertova Z, Brown C, et al. Risk of fracture in men with prostate cancer on androgen deprivation therapy: a population-based cohort study in New Zealand. BMC Cancer 2015; 15:837. www.ncbi.nlm.nih.gov/pubmed/26525985