Effectiveness of Androgen-Deprivation Therapy and Radiotherapy for Older Men With Locally Advanced Prostate Cancer. By Bekelman et al 2015
Key sentence from the paper: “[W]e found that ADT plus RT was associated with survival benefits of similar magnitude in elderly men age 76 to 85 years with locally advanced prostate cancer and older men age 65 to 85 years with screen-detected high–risk prostate cancer.”
For the full abstract, see: http://www.ncbi.nlm.nih.gov/pubmed/25559808
Commentary: Often when a patient is elderly, say, 80 years old, and found to have locally advanced prostate cancer (i.e., with his disease extending beyond the confines of his prostate gland) he is offered ADT as a solitary treatment. This study suggests that, if such patients have no other serious comorbidities, they will benefit from using some radiotherapy along with the ADT.
Bekelman JE, Mitra N, Handorf EA, Uzzo RG, Hahn SA, Polsky D, Armstrong K. 2015. Effectiveness of Androgen-Deprivation Therapy and Radiotherapy for Older Men With Locally Advanced Prostate Cancer. Journal of Clinical Oncology. [Epub ahead of print] 5 January 201