Key sentence from the paper: “ADT was significantly associated with an increased risk of any fracture and hip fracture requiring hospitalisation.”
Read MoreIs a 6 month injection of a drug like Lupron as good as a 3 month injection?
Key sentence from the paper: “[a 6-month depot formulation of Lupron] was not inferior to [a 3-month depot formulation of Lupron] for the suppressive effect on serum testosterone level.”
Read MoreHow long can one survive on ADT?
Key sentence from the paper: “…1-year relative survival ranging from 93% to 96% and 5-year relative survival between 71% and 78%.”
Read MoreWhy does ADT increase the risk of cardiovascular disease?
Key sentence from the paper: “We have seen the pendulum of ADT-associated cardiovascular disease swinging back and forth for almost a decade, and until a study is designed to directly answer the question of ADT’s role in cardiovascular disease, the pendulum will keep on swinging.”
Read MoreIs the long term burden of ADT plus radiotherapy worse than ADT alone?
Key sentence from the paper: “The addition of radiotherapy to ADT for patients with locally advanced prostate cancer significantly improved overall survival and had only modest and transient negative impact on relevant domains of health-related quality of life [outcomes].”
Read MoreDoes prostate cancer progress faster for advanced patients with diabetes on ADT?
Key sentence from the paper: “Diabetes mellitus may have a detrimental effect on progression of advanced prostate cancer, particularly in those patients with radiographic evidence of metastases.”
Read MoreWith over-prescribing ADT in the US, are all patients treated equally?
Key sentence from the paper: “Increased age, greater comorbidity, being in a racial/ethnic minority, high primary care utilization in the prior year and receiving a radiation oncology consultation before treatment were associated with increased odds of gonadotropin releasing hormone agonist overuse.”
Read MoreEthnic difference may exist in the efficacy and adverse effects of ADT
Key sentence from the paper: “In terms of adverse effects, including bone loss, cardiovascular risk, and other factors, ADT appeared to be better tolerated in Japanese than Western populations.”
Read MoreYet again, ADT is linked to metabolic syndrome and diabetes
Key sentence from the paper: “The results [of this study] suggest a 75% increased risk of metabolic syndrome and a 36% increased risk of diabetes following ADT for men with prostate cancer.”
Read MoreDoes a healthy lifestyle help for patients already on ADT?
Key sentence from the paper: “A 6-month diet and physical activity intervention can minimize the adverse body composition changes associated with ADT.”
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